For a new patient with hypertension who is intolerant to ACE inhibitors, which antihypertensive class is safest to initiate?

Study for the Board Certified Cardiology Pharmacist Exam. Utilize flashcards and answer multiple-choice questions with detailed explanations. Prepare efficiently for your certification!

Initiating treatment for a new patient with hypertension who is intolerant to ACE inhibitors is crucial and should consider the safety profile of alternative classes. In this context, angiotensin II receptor blockers (ARBs) are a suitable choice.

ARBs work by blocking the action of angiotensin II at its receptor site, which leads to vasodilation and a decrease in blood pressure. They share a similar mechanism to ACE inhibitors but do not typically cause the same side effects, such as cough or angioedema, that some patients experience with ACE inhibitors. This makes ARBs a compelling option for patients unable to tolerate ACE inhibitors due to these adverse effects.

In contrast, while calcium channel blockers, beta-blockers, and thiazide diuretics are also effective antihypertensives, they do not directly address the reason for avoiding ACE inhibitors in this scenario. Calcium channel blockers might not have the renal protective effects that ARBs offer, especially relevant for patients with kidney issues. Beta-blockers are generally not first-line therapy for hypertension unless there are specific comorbidities such as heart failure or ischemic heart disease. Thiazide diuretics are effective but can cause electrolyte imbalances, which may not be ideal for all

Subscribe

Get the latest from Examzify

You can unsubscribe at any time. Read our privacy policy