For a patient with a LDL-C of 85 mg/dL and an ASCVD risk of 8%, which statin dosage is most appropriate?

In this scenario, the choice of atorvastatin 10 mg daily is appropriate for a patient with an LDL-C level of 85 mg/dL and an ASCVD risk of 8%. Atorvastatin is a high-intensity statin that has been shown to significantly reduce cardiovascular events in patients at risk for atherosclerotic cardiovascular disease (ASCVD).

The goal of statin therapy is not only to lower LDL cholesterol but also to reduce the overall risk of cardiovascular events. Statins play a crucial role in both primary and secondary prevention strategies. In the case of a patient with an ASCVD risk of 8%, this risk suggests that the patient may benefit from moderate-intensity or higher statin therapy to further reduce their risk.

Atorvastatin at a dose of 10 mg is classified as moderate-intensity statin therapy, which is generally recommended for patients with an ASCVD risk of 20% or higher, but can also be beneficial for patients in lower risk categories to provide additional protection, especially if there are other risk factors present. Additionally, atorvastatin is often chosen due to its potency and proven effectiveness in reducing LDL cholesterol and cardiovascular risk.

The other options listed (fluvastatin, simvast