In the context of anticoagulation therapy for patients with mechanical valves, what is the recommended INR goal after a thromboembolic event due to valve thrombosis?

The recommended INR goal after a thromboembolic event due to valve thrombosis in patients with mechanical valves is established to ensure adequate anticoagulation while minimizing the risk of further clot formation. For patients with mechanical heart valves, particularly those who have experienced thrombosis, maintaining a higher INR range is critical to preventing additional thromboembolic complications.

An INR goal of 3.5-4.0 is specifically recommended in this context due to the higher risk associated with mechanical valve thrombosis and the need for more intensive anticoagulation. This range helps to ensure that the anticoagulation levels are sufficiently elevated to dissolve existing clots and prevent new ones from forming, especially in high-risk populations.

Therefore, the selection of this INR goal reflects clinical guidelines that prioritize the management of anticoagulation in patients who have demonstrated a propensity for thrombus formation on their mechanical valves.