What is the best combination of medications to add for a 57-year-old woman with elevated blood pressure and a history of diabetes who's currently on metformin?

The best choice for this scenario, which involves a 57-year-old woman with elevated blood pressure and a history of diabetes who is currently on metformin, is the combination of lovastatin and amlodipine.

This patient’s background of diabetes and elevated blood pressure requires a comprehensive approach to her management. The use of amlodipine, a calcium channel blocker, is beneficial for treating hypertension, particularly in patients with diabetes, as it helps lower blood pressure effectively and protects against cardiovascular events. Additionally, the choice of lovastatin addresses the dyslipidemia often present in patients with diabetes. Statins like lovastatin are indicated to reduce cardiovascular risk in individuals with diabetes, given their potential to lower LDL cholesterol and stabilize atherosclerotic plaques.

The proposed combination not only targets her hypertension but also promotes cardiovascular health, aligning with the current guidelines for managing patients with diabetes who are at a higher risk for cardiovascular complications. This comprehensive approach helps provide better long-term outcomes by addressing both blood pressure and lipid levels, alongside existing metformin therapy for glucose management.

Other options may not effectively address both hypertension and cardiovascular risk simultaneously. While some may provide partial benefits, the combination of amlodipine and lovastatin ensures a focused approach