What is the most likely factor for a 70-year-old woman presenting with worsening dyspnea due to acute decompensated heart failure?

Study for the Board Certified Cardiology Pharmacist Exam. Utilize flashcards and answer multiple-choice questions with detailed explanations. Prepare efficiently for your certification!

In the context of acute decompensated heart failure, the most likely factor contributing to the worsening dyspnea in a 70-year-old woman is related to the adjustment of her β-blocker dosage. Although β-blockers are beneficial for patients with heart failure due to their ability to improve heart function and reduce mortality, rapid increases in the dosage may lead to an exacerbation of heart failure symptoms, such as worsening dyspnea.

When a patient is started on a β-blocker or has their dose escalated too quickly, it can lead to negative effects on cardiac output, particularly if the patient is not adequately compensated or if they have underlying vulnerabilities. This situation can result in symptoms of heart failure getting worse, specifically with increased fluid retention and subsequent dyspnea.

The other factors, while they can contribute to heart failure exacerbations, are less likely to be the primary cause in this particular scenario. For instance, inadequate blood pressure control may impact heart failure but does not directly cause acute decompensation like a rapid dose change of a medication designed to manage the condition. Nonadherence to diuretic therapy typically manifests with fluid overload over time, and digoxin toxicity, while serious, is less common compared to inappropriate adjustments of heart failure

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