What is the target INR range for patients on warfarin therapy for atrial fibrillation?

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The target INR range for patients on warfarin therapy for atrial fibrillation is typically 2.0 to 3.0. This range is established to effectively reduce the risk of thromboembolic events, such as stroke, while minimizing the risk of bleeding complications associated with anticoagulation therapy.

Clinical guidelines indicate that maintaining the INR within this range provides a good balance between efficacy and safety. For patients with atrial fibrillation, an INR lower than 2.0 may not sufficiently prevent thromboembolic complications, while an INR above 3.0 increases the risk of bleeding.

Monitoring and dose adjustments are essential components of warfarin therapy to ensure that patients remain within this therapeutic range, especially as various factors, including diet, medications, and comorbid conditions, can influence INR levels. Therefore, targeting an INR of 2.0 to 3.0 is the standard approach for optimizing treatment outcomes in atrial fibrillation management with warfarin.

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